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Evidence of Face Masks and Masking Policies for the Prevention of SARS-CoV-2 Transmission and COVID-19 in Real-World Settings: A Systematic Literature Review

doi.org · added Oct 2026

Summary

Of 2,616 records, 79 studies of mask wearing or mask policies in real-world settings met the criteria (search to June 2023). 61 of them (77%) reported that masks or mask policies reduced SARS-CoV-2 transmission or COVID-19, with similar shares across study designs, mask types and settings.

Key points

  • Of 2,616 records, 79 studies met the criteria: 43% in community settings, 38% in health care and 19% in schools or universities.
  • 61 studies (77%) reported evidence that mask wearing or mask policies reduced SARS-CoV-2 transmission or COVID-19.
  • The share reporting benefit was similar across study designs (67% to 100%), mask types (77% to 100%) and settings (80% to 91%); 85% of masking-policy studies reported a benefit.
  • The review counted studies for or against an effect (vote counting) rather than pooling effect sizes.
  • Design: systematic review following PRISMA guidelines, searched to June 2023.
  • Funding: Conrad Prebys Foundation and NIMHD (NIH); no conflicts declared.