Summary
In 63 ventilated intensive care unit patients, oral mucosa scores were similar across arms for three days. From day four, ozonated water scored better than both HOCl and chlorhexidine, with HOCl described as moderately protective against chlorhexidine.
Key points
- Design: randomized controlled trial, 3 arms, 7 days. The outcome is oral mucosal integrity, not respiratory infection.
- Funding: not checked.
- Added from the October 2026 literature sweep, from the abstract; curators to check against the full text.