Summary
Rats breathing HOCl gas at 0.75 and 1.79 ppm for 4 hours showed raised levels of enzymes linked to cell damage. The authors say HOCl gas at these concentrations causes pronounced oxidative stress in animals and call for more study.
Key points
- Single 4-hour whole-body exposure at 0.75 and 1.79 ppm.
- Cathepsins B and H rose, H by 1.6 to 6.4 times; alpha-1 antitrypsin rose.
- "Pronounced oxidative stress" in animals.
- Independent university team; abstract read.