Summary
A 2025 review finds saline and tap water prevent infection in acute wounds, while antiseptics including hypochlorous acid and sodium hypochlorite show promise in chronic wounds.
Key points
- In acute wounds, saline and potable tap water effectively prevent infection.
- In chronic wounds such as diabetic foot ulcers and pressure injuries, hypochlorous acid, sodium hypochlorite, polyhexanide and citrate-based solutions have shown promise for healing and infection.
- The review covers labeling and concentrations from FDA sources and identifies gaps in the evidence.
- Antibiotic stewardship and cytotoxicity concerns are changing practice.