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Povidone-iodine nasal rinse and mouthwash in COVID-19 management: a prospective randomised pilot trial

pmc.ncbi.nlm.nih.gov · added Oct 2026

Summary

Among 19 participants, mean time of viral survival was 9.8 days with 0.23% povidone-iodine, 12 days with saline and 12.6 days with no intervention (p=0.046). Cycle-threshold changes and quality-of-life scores did not differ between groups, and the sample is very small.

Key points

  • Design: Open-label randomized pilot, three arms.
  • Funding: none reported; no competing interests.
  • Added from the October 2026 literature sweep, from the abstract; curators to check against the full text.