The effects of neutrophil-generated hypochlorous acid and other hypohalous acids on host and pathogens

Created

Sep 3, 2023 8:20 PM

Type

medical studyjournal article

Publication

Summary

This article explores the effects of hypochlorous acid, generated by neutrophils, on both the host and pathogens in the body.

Key Points

- Neutrophils are immune cells that produce hypochlorous acid (HOCl) and other hypohalous acids (HA). - HOCl and HA are toxic to pathogens, but can also damage host tissues. - The effects of HOCl and HA depend on their concentration and the context in which they are produced. - Understanding the balance between the beneficial and harmful effects of HOCl and HA can help develop new therapies for infectious and inflammatory diseases.

super:Link

https://link.springer.com/article/10.1007/s00018-020-03591-y

Date

Notes

Attachment

Source

This is from SpringerLink in 2020 at https://link.springer.com/article/10.1007/s00018-020-03591-y

Keywords

Keywords: neutrophils, hypochlorous acid, hypohalous acids, host-pathogen interactions, oxidative stress

Created time

Sep 3, 2023 8:20 PM