This article explores the effects of hypochlorous acid, generated by neutrophils, on both the host and pathogens in the body.
- Neutrophils are immune cells that produce hypochlorous acid (HOCl) and other hypohalous acids (HA). - HOCl and HA are toxic to pathogens, but can also damage host tissues. - The effects of HOCl and HA depend on their concentration and the context in which they are produced. - Understanding the balance between the beneficial and harmful effects of HOCl and HA can help develop new therapies for infectious and inflammatory diseases.
This is from SpringerLink in 2020 at https://link.springer.com/article/10.1007/s00018-020-03591-y
Keywords: neutrophils, hypochlorous acid, hypohalous acids, host-pathogen interactions, oxidative stress
