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Benefits and side effects of nasal irrigation in severe asthma

Benefits and side effects of nasal irrigation in severe asthma

Created
Sep 8, 2023 5:18 PM
Type
medical studyjournal articlenasal irrigationsevere asthmarhinosinusitis
Publication
Summary

Nasal irrigation can significantly improve nasal and chest symptoms in patients with severe asthma, making it an effective and low-cost treatment option with minimal side effects.

Key Points

- Nasal irrigation improves nasal symptoms in 88% of severe asthma patients. - 62% reported improvement in chest symptoms. - Statistically significant reductions in SNOTT and ACQ scores after treatment. - Few side effects reported; effective and inexpensive intervention. - Should be recommended in severe asthma clinics.

super:Link
https://thorax.bmj.com/content/71/Suppl_3/A151.3
Date
Notes

Attachment
Source

This is from Journal in 2023 at https://thorax.bmj.com/content/71/Suppl_3/A151.3

Keywords

nasal irrigation, severe asthma, rhinosinusitis, symptoms improvement, side effects

Created time
Sep 8, 2023 5:18 PM

Abstract

Introduction and aim Rhinosinus disease is common in asthma and causes nasal congestion, post nasal drip and pain. This can lead to altered breathing patterns, particularly mouth breathing which exposes patients airways to cold dehumidified air and may aggravate their asthma. Nasal irrigation is accepted as an appropriate early intervention for managing allergic rhinitis but may be under-utilised in severe asthma. This study aims to evaluate the effects of nasal irrigation in a severe asthma population.

Method Thirty patients (23 females, mean age 47), with a confirmed diagnosis of severe asthma (22/30 73% atopic) and rhinosinusitis took part in this study, none of the participants had previous nasal irrigation. Patients were taught to irrigate with the netti pot system (0.9%saline), initially 1–2 times each day and to titrate to individual needs. Symptoms were assessed with snott-22 questionnaires before and after three months of treatment, snott scores range from 0–110, a difference of 8.9 points is the minimal change thought to be clinically significant. Data was also collected on ACQ scores, usage, reported benefits and side effects.

Results 26 patients were using nasal irrigation at three month follow-up, mean initial snott scores were 63.2 ± 22.9 compared to 41.7 ± 26.8 post treatment (p = 0.0001). 69% (18/26) patients showed clinically significant decreased nasal symptoms, with a mean improvement of 33.7 points. 19% (5/26) showed no significant change and 12% (3/26) had a clinically significant increase in nasal symptoms. 88% (23/26) patients felt their nasal symptoms had improved, 62% (16/26) felt their chest symptoms had improved. Mean initial ACQ 3.42 ± 1.39 compared to 2.62 ± 1.58 post treatment (p = 0.01). Usage ranged from BD to 3–5 times per week. 17% (5/30) of patients reported side effects: headache (2) sneezing(1) Nose bleed(1) LBP(1) three patients stopped treatment due to the side effect.

Conclusion After three months of nasal irrigation 88% of patients reported improved nasal symptoms, 62% reported improved chest symptoms, there were statistically significant improvements in mean snott 22 and ACQ scores. Nasal irrigation is therefore an effective and inexpensive intervention, with few side effects, in the treatment of rhinosinus and related asthma symptoms and should be advocated in severe asthma clinics.

image

Abstract P127 Figure 1

Changes in SNOTT score with nasal irrigation treatment

http://dx.doi.org/10.1136/thoraxjnl-2016-209333.270

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