This study found that nasal irrigation with normal saline and various solutions is effective in reducing symptoms and endoscopic scores for chronic rhinosinusitis patients after functional endoscopic sinus surgery, but no significant difference was found in symptom scores or endoscopic scores when comparing different solutions to normal saline.
- Nasal irrigation is an effective therapy for chronic rhinosinusitis patients after functional endoscopic sinus surgery. - Various solutions are more effective than normal saline alone in reducing eosinophil count. - No significant difference was found in symptom scores or endoscopic scores when comparing various solutions with normal saline.
This is from Journal of Laryngology and Otology in 2023 at https://www.cambridge.org/core/journals/journal-of-laryngology-and-otology/article/abs/effects-of-nasal-irrigation-with-various-solutions-after-endoscopic-sinus-surgery-systematic-review-and-metaanalysis/39E1FB2F43D7D981A7D613D87428AA1E.
Keywords: - Nasal Lavage - Endoscopy - Chronic Rhinosinusitis - Meta-analysis - Systematic review
Abstract
Background
Nasal irrigation is commonly performed in patients with chronic rhinosinusitis after functional endoscopic sinus surgery. This study systematically assessed the clinical efficacy of nasal irrigation from the medical literature.
Methods
The PubMed, Embase and Cochrane Central Register of Controlled Trials databases were searched using a comprehensive strategy, limited to English-language articles, published from October 1971 to March 2017, and comprising human subjects.
Results
A total of 824 trials were identified, 5 of which, involving 331 participants, were included in this systematic review. After selection, only three trials were eligible for inclusion in a meta-analysis. Nasal irrigation using normal saline and various solutions was found to be effective in reducing symptom scores and endoscopic scores for chronic rhinosinusitis patients after functional endoscopic sinus surgery. Comparison of outcome measures, such as eosinophil count reduction, revealed that various solutions are more effective than normal saline alone; however, no statistical significance was found in terms of reduced symptom or endoscopic scores.
Conclusion
Based on the current limited evidence, nasal irrigation is an effective therapy for chronic rhinosinusitis patients after functional endoscopic sinus surgery. However, when comparing various solutions with normal saline, no significant difference was found in symptom scores or endoscopic scores.
Keywords
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